Monkeypox was first identified in humans in 1970. The first known human case occurred in Democratic Republic of Congo. Between the year 1970 and 1971, similar cases occurred in Ivory Coast, Liberia, Nigeria and Sierra Leone.
The virus was first identified in the State Serum Institute in Copenhagen, Denmark, in 1958 during an investigation into a pox-like disease among monkeys.
Monkeypox was limited to the rainforests of Central and Western Africa. Most reported cases confirmed direct contact or exposure to ill prairire dogs showing signs of profuse nasal discharge, ocular discharge, dyspnea and lymphadenopathy.
The first outbreak occurred in the United State in the spring of 2003. Monkeypox cases were confirmed on the basis of isolation or detection of the virus by Polymerase Chain Reaction (PCR).
Individuals who are infected presented with fever and rash within 21days of exposure. The virus have no racial predilection and the incidence is equal in both sexes.
The prognosis is good to excellent, if detected and reported early. But may decrease in immune compromised patients.